The greatest American heroes are back, and they've been set up to take the fall for a terrible crime they didn't commit. Now, Roadblock, Duke, and the other G.I. Joes must once again face their mortal enemy, COBRA, as well as dangerous new threats operating within the government. When all else fails, one option remains: retaliation.

A charming thief and a band of unlikely adventurers undertake an epic heist to retrieve a lost relic, but things go dangerously awry when they run afoul of the wrong people in this hilarious and action-packed adventure.

Weapons expert James McCullen has created a nanotechnology-based weapon capable of destroying an entire city. His company MARS sells four warheads to NATO, and the U.S. Army is tasked with delivering the warheads. Duke and Ripcord are delivering the warheads when they are ambushed by the Baroness. The two are rescued by Scarlett, Snake Eyes and Heavy Duty. They take the warheads to the G.I. Joe's command center, rendezvousing with General Hawk. McCullen...